Wednesday, February 28, 2007

Hypertension recommendations after stroke

The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC7) provided several new guidelines for hypertension prevention and management (Chobanian, 2004; Table 6). Some of the updates included:

  • Thiazide-type diuretics should be used to treat most patients with uncomplicated hypertension, either alone or combined with drugs from other classes. Certain high-risk conditions are compelling indications for the initial use of other antihypertensive drug classes (angiotensin-converting enzyme inhibitors, angiotensin-receptor blockers, beta-blockers, calcium channel blockers)
  • Most patients with hypertension will require two or more antihypertensive medications to achieve goal blood pressure (<140/90 mm Hg or <130/80 mm Hg for patients with diabetes or chronic kidney disease)
  • If blood pressure is more than 20/10 mm Hg above goal, consideration should be given to initiating therapy with two agents, one of which usually should be a thiazide-type diuretic
  • even in normotensive patients, further reduction of blood pressure should be contemplated unless they have a high grade arterial stenosis.









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