GESICA study of nat history of intracranial stenosis

M et al. Prospective study of Symptomatic Intracranial atherothrombotic intracranial stenoses: The Gesica study This is a natural history study of patients with intracranial stenosis of one or more vessel of more than 50 percent. 27 percent had clinical hemodynamic symptoms, After about two years, 14 percent had stroke and 24 percent TIA, but sixty percent had recurrent stroke when hemodynamic symptoms were present. This may be a subset of stroke patients for consideration for more aggressive treatments. Angioplasty was done in patients with antecedent tia (62 %) or stroke (37 %) with mean time to performance of 1.5 months. Periprocedure complication rate was 14 %. In this study of 102 patients with disease in all intracranial arteries, symptomatic ICAS failing medical therapy had a stroke rate up to 55 % within 36 days