few aspirin studies in stroke with a few of take away points

Dutch trial 1991  30 mg aspirin was as good as 283 mg
CAST  aspirin was better than placebo
MATCH   aspirin plus Plavix had little increased benefit but more bleeding
CHANCE trial  Chinese trial favored dual antiplatelet drugs for 90 days
IST trial 1997-- aspirin in first 48 hours led to better outcome
CAPRIE trial clopidogrel was superior to aspirin IF peripheral vascular disease is present otherwise they are same
CHARISMA trial  Dual antiplatelet treatment is dangerous for primary prevention
ESPS 2  Aggrenox was superior to aspirin alone.
PROFESS trial 2007  Aggrenox v. Plavix showed no difference between the two