Sunday, March 31, 2019

Neonates with strokes hypercoagulable associations

59 percent have one or more prothrombotic risk factors esp. increased lipoprotein (a) (45/125, then Factor V leiden  (32/125) or protein S deficiency (one patient) which is much more rare

1:4000 term babies have strokes usually MCA left more than right due to flow with PDA Patent ductus arteriosus

half are normal later in infancy

Stroke mortality is dramatically higher in neonates with high death rate especially for ICH

Catheters cause 80 percent of deep vein thrombosis in newborns, 60 percent inolder children.  Noncatheter associated arterial thrombosis is rare

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