Faris et al. Sneddon's syndrome without antiphospholipid antibodies: a report of 26 cases with cerebral angiography (Rabat). Neurology 2010 74:9:PO2:099.
Authors emphasize Sneddon's syndrome (stroke plus livedo racemosa) is NOT identical to APL syndrome. 26 patients were studied retrospectively with a combination of focal motor deficits and dementia. Imaging always showed infarcts with white matter involvement. Angio showed a distal arteriopathy in 18 cases with pial networks in cases. Two had hematomas. The authors suggested angiography to prevent the unwarranted and dangerous potential use of anticoagulation.
Authors emphasize Sneddon's syndrome (stroke plus livedo racemosa) is NOT identical to APL syndrome. 26 patients were studied retrospectively with a combination of focal motor deficits and dementia. Imaging always showed infarcts with white matter involvement. Angio showed a distal arteriopathy in 18 cases with pial networks in cases. Two had hematomas. The authors suggested angiography to prevent the unwarranted and dangerous potential use of anticoagulation.
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