D-dimer assay may differentiate subtypes of ischemic stroke; study of 126 patients hospitalized with acute ischemic stroke;
stroke subtypes were cardioembolic in 34 (27%),
atherothrombotic in 34 (27%),
lacunar in 31 (25%),
unknown in 27 (21%);
mean D-dimer levels on day 1 were 2.96 mcg/mL with cardioembolic stroke, 1.34 mcg/mL with atherothrombotic stroke and 0.67 mcg/mL with lacunar stroke; similar results at days 6 and 12; D-dimer > 2 mcg/mL had 59% sensitivity and 93% specificity for predicting cardioembolic stroke, D-dimer < 0.54 mcg/mL had 61% sensitivity and 96% specificity for predicting lacunar stroke
(Arch Intern Med 2002 Dec 9/23;162(22):2589)
stroke subtypes were cardioembolic in 34 (27%),
atherothrombotic in 34 (27%),
lacunar in 31 (25%),
unknown in 27 (21%);
mean D-dimer levels on day 1 were 2.96 mcg/mL with cardioembolic stroke, 1.34 mcg/mL with atherothrombotic stroke and 0.67 mcg/mL with lacunar stroke; similar results at days 6 and 12; D-dimer > 2 mcg/mL had 59% sensitivity and 93% specificity for predicting cardioembolic stroke, D-dimer < 0.54 mcg/mL had 61% sensitivity and 96% specificity for predicting lacunar stroke
(Arch Intern Med 2002 Dec 9/23;162(22):2589)
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